Way of Synthesis Evolution of Design and Methods for Natural Products

At the center of organic chemistry is the effective synthesis of natural products or compounds, which are important for pharmaceuticals and agrochemicals, for example. These syntheses often include new reactions and novel concepts in organic chemistry, such that there is always a need for innovative strategies and improved methods. This textbook presents not only synthetic ways to design organic compounds, it also contains a compilation of total synthesis with a comparative view of multiple designs for the same targets. It explains different tactics and strategies, making it easy to apply to many problems, whatever the synthetic question in hand. Following a historical view of the evolution of synthesis, the book goes on to look at principles and issues impacting synthesis and design as well as principles and issues of methods. The sections on comparative design cover classics in terpenes and alkaloid synthesis, while a further section covers such miscellaneous syntheses as Maytansine, Palytoxin, Brevetoxin B and Indinavir. The whole is rounded off with a look at future perspectives. With its attractive layout highlighting key parts and tactics using a second color this is a useful tool for organic chemists, lecturers and students in chemistry, as well as those working in the chemical industry.Reed, Josephine W. is the author of 'Way of Synthesis Evolution of Design and Methods for Natural Products', published 2007 under ISBN 9783527320776 and ISBN 3527320776.