Understanding Electrophoresis of Macromolecules

Electrophoresis is a key method in modern bioanalytics, with a broad range of applications, in particular for the separation and characterization of such biomolecules as proteins and nucleic acids, but also for other macromolecules. This book covers the fundamentals of electrophoresis, providing a complete overview of the physical mechanisms underlying this technique. The two authors -- acknowledged experts in their field -- present the text in such a way as to allow a full understanding for advanced students, while also making this a handy reference for every practitioner of electrophoresis. The first part represents an introduction to general concepts, followed by separation by size and other criteria for charged macromolecules. The final part includes an introduction to the principles of miniaturization used for lab-on-chips and micro total analysis systems. Numerous illustrations, many in color, are used throughout the book, and other useful features include an appendix of modeling and simulation methods and a compilation of properties of commonly used gels and polymers. The whole is rounded off by an overview of the relevant literature and a comprehensive list of references.Viovy, Jean-Louis is the author of 'Understanding Electrophoresis of Macromolecules', published 2009 under ISBN 9783527312535 and ISBN 3527312536.