Third Histamine Receptor Selective Ligands As Potential Therapeutic Agents in Cns Disorders

Since their initial discovery, the potential of histamine H 3 receptor ligands in various disorders of the central nervous system has been an area of great interest. The Third Histamine Receptor presents the most recent advances in this area, with an emphasis on pharmacology. It provides a single source of information covering the identification and localization of H 3 receptor, as well as the development of novel ligands incorporating pre-clinical and recent clinical studies indicating the earliest possible stage of development of these ligands. The book includes a general overview of histamine as a neurotransmitter in the brain, and with significant detail covers receptor pharmacology, signal transduction, selective ligands, and therapeutic potential in peripheral disorders. Several chapters address various CNS disorders in which H 3 receptors are known to play a major role, including cognitive function disorders such as Alzheimer's disease, ADHD, sleep disorders, epilepsy, obesity, neuropsychiatric disorders, and neurodegenerative disorders.Vohora, Divya is the author of 'Third Histamine Receptor Selective Ligands As Potential Therapeutic Agents in Cns Disorders', published 2008 under ISBN 9781420053920 and ISBN 1420053922.