Cytokine Handbook

The fourth edition of The Cytokine Handbook provides an encyclopedic coverage of the molecules that induce and regulate immune responses. Now expanded to two volumes, co-edited by Michael T Lotze, and written by over 120 international experts, the scope of the book has been broadened to include a major emphasis on the clinical applications of cytokines. The early chapters discuss individual cytokines, chemokines and receptors, including the IL-1 family, the extended IL-10 family (including IL-19, IL-20, and IL-22), the IL-12 family (including IL-23 and IL-27), the EGF Family, MIF, and HMGB1. These are grouped by cytokine families, many of which have recently been revealed by the availability of new sequence data arising from the human genome project. Additional chapters discuss the clinical implications and applications of cytokines, including cytokine gene transfer, antisense therapy and assay systems. This book is essential for researchers and clinicians interested in cytokines, including anyone working in cancer biology, transplantation, infectious diseases, autoimmunity or bioinformatics. Reviews of previous editions: "The Cytokine Handbook has bought together a number of internationally recognized scientists to detail and synthesize a wealth of information on cytokine biology in a much needed and most readable and highly referenced book." IMMUNOLOGY TODAY "...an excellent guide to the novice to find a way into the cytokine maze, or for the experienced researcher to become updated." MICROBIOLOGY TODAY "The Cytokine Handbook provides a comprehensive introduction to these cell-modulating proteins, with contents that are of interest not only to the uninitiated but also to those already hooked." NATUREThomson, Angus W. is the author of 'Cytokine Handbook', published 2003 under ISBN 9780126896633 and ISBN 0126896631.