Biological Specimen Preparation for Transmission Electron Microscopy

This book contains all the necessary information & advice for anyone wishing to obtain electron micrographs showing the most accurate ultrastructural detail in thin sections of any type of biological specimen. The guidelines for the choice of preparative methods are based on an extensive survey of current laboratory practice. For the first time, in a textbook of this kind, the molecular events occurring during fixation & embedding are analysed in detail. The reasons for choosing particular specimen preparation methods are explained & guidance is given on how to modify established techniques to suit individual requirements. All the practical methods advocated are clearly described, with accompanying tables & the results obtainable are illustrated with many electron micrographs. Portland Press Series: Practical Methods in Electron Microscopy, Volume 17, Audrey M. Glauert, EditorPeter R. Lewis is the author of 'Biological Specimen Preparation for Transmission Electron Microscopy', published 1998 under ISBN 9780691007496 and ISBN 0691007497.