Bioinformatics From Genomes to Therapies

Once again, Thomas Lengauer has succeeded in creating a comprehensive and immensely useful resource that meets even the high standards of professionals in the pharmaceutical and medical sector. By extending the classical application areas of bioinformatics to the latest approaches in analyzing molecular networks and predicting molecular function, this handbook serves as a one-stop resource for every bioinformatics user in the life and medical sciences. With contributions by more than 80 of the world's leading bioinformaticians, it is unrivalled in terms of both scientific authority and accuracy. Its coverage extends beyond the biological background and methodological basics to include such topical aspects as the optimization of drug leads, personalization of drug therapies, and disease-specific applications, such as bacterial or viral infections, supported by numerous references to bioinformatics software and data resources throughout. The best single information source available-written by professionals for professionals. Thomas Lengauer is Director of the Max-Planck Institute for Informatics in Saarbrucken, Germany. He has been involved in computational biology research since the beginning of the 1990s, focusing on protein bioinformatics, computational drug screening and design, as well as bioinformatics for understanding and curing diseases. He is a founding member of the International Society for Computational Biology (ISCB), a member of the steering board of the international conference series RECOMB, and headed the steering board of the European bioinformatics conference series ECCB since its foundation in 2002 until 2005. In 2001 he co-founded BioSolveIT GmbH, which develops and distributes chemoinformatics software. A member of the German Academy of Sciences Leopoldina, in 2003 Professor Lengauer received the Konrad Zuse Medal of the German Informatics Society and the Karl Heinz Beckurts Award.Lengauer, Thomas is the author of 'Bioinformatics From Genomes to Therapies', published 2007 under ISBN 9783527312788 and ISBN 3527312781.